DropletMicroarray: facile formation of arrays of microdroplets and hydrogel micropads for cell screening applications.

نویسندگان

  • Erica Ueda
  • Florian L Geyer
  • Victoria Nedashkivska
  • Pavel A Levkin
چکیده

We describe a one-step method for creating thousands of isolated pico- to microliter-sized droplets with defined geometry and volume. Arrays of droplets are instantly formed as liquid moves along a superhydrophilic-superhydrophobic patterned surface. Bioactive molecules, nonadherent cells, or microorganisms can be trapped in the fully isolated microdroplets for high-throughput screening, or in hydrogel micropads for screening in 3D microenvironments.

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عنوان ژورنال:
  • Lab on a chip

دوره 12 24  شماره 

صفحات  -

تاریخ انتشار 2012